Structure and Bioactivity of Sulfated Polysaccharides

Structure versus anticoagulant and antithrombotic actions of marine sulfated polysaccharides

Marine sulfated polysaccharides (MSP), such as sulfated fucans (SF), sulfated galactans (SG) and glycosaminoglycans (GAG) isolated from either algae or invertebrate animals, are highly anionic polysaccharides capable of interacting with certain cationic proteins, such as (co)-factors of the coagulation cascade during clotting-inhibition processes. These molecular complexes between MSP and coagu...

Isolation, Bioactivity and Applications of Sulfated Polysaccharides from Poultry By- Products

Effects of sulfated polysaccharides on tumour biology.

Sulfated polysaccharides can act not only as anticoagulants but also as tumour inhibitors. Recent studies suggest that sulfated polysaccharides could affect tumour cells directly. Sulfated polysaccharides could inhibit the metastasis and proliferation of tumour cells by binding to growth factors and cell adhesion molecules. Moreover, sulfated polysaccharides could inhibit heparanase, which clea...

[Neuroprotective effects of sulfated polysaccharides from seaweed].

Currently, neurodegenerative diseases (NDD) occupy a significant place in the structure of disease of the elderly, which dictates the need to find new and effective treatment and prevention of this pathology. At the heart of NDD development is a violation of the metabolism and the conformational change of cellular proteins with subsequent accumulation and aggregation of their in certain groups ...

Microwave-assisted extraction of sulfated polysaccharides